4 edition of Cardiovascular specific gene expression found in the catalog.
Cardiovascular specific gene expression
Includes bibliographical references and index.
|Statement||edited by Pieter A. Doevendans, Robert S. Reneman, Marc van Bilsen.|
|Series||Developments in cardiovascular medicine -- 214|
|Contributions||Doevendans, Pieter A., Reneman, R. S., Bilsen, Marc van.|
|LC Classifications||QP110.G45 C37 1999|
|The Physical Object|
|Pagination||xiii, 327 p. :|
|Number of Pages||327|
|LC Control Number||99013442|
Title: Tissue-Specific Targeting for Cardiovascular Gene Transfer. Potential Vectors and Future Challenges. VOLUME: 4 ISSUE: 4 Author(s):Caroline Beck, Hidetaka Uramoto, Jan Boren and Levent M. Akyurek Affiliation:Department of Anatomy and Cell Biology, Goteborg University, Medicinaregatan , Box , SE Goteborg, Sweden. Keywords:gene transfer, bispecific antibody, promoter Cited by: Differences in cardiovascular diseases are evident in men and women throughout life and are mainly attributed to the presence of sex hormones and chromosomes. Epigenetic mechanisms drive the regulation of the biological processes that may lead to CVD and are possibly influenced by sex. In order to gain an overview of the status quo on sex differences in cardiovascular epigenetics, we Cited by: 5.
Title: Tissue-Specific Targeting for Cardiovascular Gene Transfer. Potential Vectors and Future Challenges. VOLUME: 4 ISSUE: 4 Author(s):Caroline Beck, Hidetaka Uramoto, Jan Boren and Levent M. Akyurek Affiliation:Department of Anatomy and Cell Biology, Goteborg University, Medicinaregatan , Box , SE Goteborg, Sweden. Keywords:gene transfer, bispecific antibody, promoter. Gene therapy can be broadly defined as the transfer of defined genetic material to specific target cells of a patient for the ultimate purpose of preventing or altering a particular disease state.
Gene Transfer in the Cardiovascular System Pdf The goal of gene transfer is protein expression. a process brought about by the insertion of a gene coding for a foreign protein into target cells resulting in the synthesis of the foreign protein For gene therapy, a tmnsferred therapeutic gene must be expressed at a level beneficial for the patient. In an effort to transfer MMTV-specific regulation of gene expression to a more efficient murine leukemia virus (MLV) vector, we have replaced the complete 3′ U3 region of MLV with the complete.
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Because in most cardiovascular diseases the genetic component is a consequence of more than one gene defect, only limited progress has as yet been made in identifying subjects genetically at risk. For example, in hypertension only in less than 10% of the patients the genetic defect has been identified.
Cardiovascular Specific Gene Expression. Editors: Doevendans, P.A.F.M., Reneman, Robert S., van Bilsen, Marc (Eds.) Free Preview. Machine derived contents note: List of Contributors. Preface. Cardiology Approaching the Year A Clinician's Look at Molecular Cardiology; H.J.
Wellens. Part One: Cardiovascular Specific Gene Expression. The Transcriptional Building Blocks of the Heart; D. Franco, et al. A Cardiac-Specific Troponin I Promoter.
Cardiology approaching the year A clinician\'s look at molecular cardiology -- One: Cardiovascular specific gene expression -- 2.
The transcriptional building blocks of the heart -- 3. A cardiac-specific troponin I promoter. Distinctive patterns of regulation in cultured fetal cardiomyocytes, adult heart and transgenic mice -- 4.
Cardiovascular Specific Gene Expression (Developments in Cardiovascular Medicine) [P.A.F.M. Doevendans, Robert S. Reneman, Marc van Bilsen] on *FREE* shipping on qualifying offers. Improving our insights into the genetic predisposition to cardiovascular disease is one of the most important challenges in our field in the next millennium.
Find many great new & used options and get the best deals for Developments in Cardiovascular Medicine: Cardiovascular Specific Gene Expression by Marc V. Bilsen, Robert S. Cardiovascular specific gene expression book and Peter A.
Doevendans (, Hardcover) at the best online prices at. The current human genome was moulded and refined through generations of time. We propose that the basic framework for physiologic gene regulation was selected during an era of obligatory physical activity, as the survival of our Late Palaeolithic (50 –10 BC) ancestors depended on hunting and by: Franz WM, Rothmann T, Frey N, Katus HA.
Analysis of tissue-specific gene delivery by recombinant adenoviruses containing cardiac-specific promoters. Cardiovascular Research ; – PubMed CrossRef Google ScholarAuthor: Wolfgang-Michael Franz, Thomas Rothmann, Matthias Müller, Norbert Frey, Hugo Albert Katus.
Cardiovascular aging is a complex process that involves multiple mechanisms not dependent on a single pathway or on specific genes or gene products. However, signaling and genetics research have provided major insights in our understanding of the mechanisms of aging, both in its highly conserved aspects as well as those more specific to human.
The Vascular Smooth Muscle Cell Vascular Smooth Muscle-Specific Gene Expression. Devoted entirely to the subject of SMC, the book covers a diversity of topics-from SMC architecture and contractility to differentiation and gene expression in development.
It also examines the proliferation and replication of SMC and its role in. "This collection of very detailed molecular biology protocols was compiled The first five parts present protocols that are designed to identity and characterize genes in cardiovascular disease, including methods for detecting specific gene mutation, identifying new genes, characterizing the levels and regulation of expression of the new genes.
Gene features most important for the prediction process differed for guilt-by-association (GBA) and guilt-by-profiling (GBP) predictors. For GBP, feature importance varied based on the phenotype being predicted, but tissue expression and phylogenetic relationships appeared to consistently be the most relied upon features (see supplementary material Table S1 for gene feature rankings).Cited by: The disorganization of sarcomeres could be due to a specific function of BMP-2 in regulating the expression of a subset of sarcomeric genes, or other specific alterations in gene expression that secondarily lead to sarcomeric disorganization.
BMP-2 controls MEF2A expression in the neonatal cardiac myocytesCited by: The discovery and cloning of thrombopoietin (TPO), the ligand of the myeloproliferative (Mpl) receptor, opened a new perspective in megakaryocyte differentiation studies.
This chapter focuses on reviewing studies related to the role of specific transcription factors in promoting gene expression in the megakaryocytic by: 5.
Atrial Light Chain-2 (ALC-2) also known as Myosin regulatory light chain 2, atrial isoform (MLC2a) is a protein that in humans is encoded by the MYL7 gene. ALC-2 expression is restricted to cardiac muscle atria in healthy individuals, where it functions to modulate cardiac development and human diseases, including hypertrophic cardiomyopathy, dilated cardiomyopathy, ischemic Aliases: MYL7, MYL2A, MYLC2A, myosin light chain 7.
Dear Colleagues, Gene expression and how it is regulated is a fundamental question in biology and therefore its complexity is not surprising. Initially the major focus of research was on transcription factors as the major modulators of gene expression.
Gene Therapy in Cardiovascular Disease. Gene Therapy Applications • Dishart KL, Work LM,Denby L, and Baker AH. Gene Therapy for Cardiovascular Disease. Journal of Biomedicine and Biotechnology () – • Chen ZY, Lin Y, Yang F, Jiang Land Ge SP.
Gene therapy for cardiovascular disease mediated by ultrasound and microbubbles. Notch- and Alk1-mediated control of Notch target gene expression is gene-specific and context-dependent. Whole mount in situ hybridization for tp1:egfp, hey2, efnb2a, dll4, and cdh5 in 36 hpf wt and alk1 ft09e embryos treated with 1% DMSO or 10 μmol/L LY, 23–36 by: 9.
From antioxidants to Cardiovascular Index to gene expression. Excerpt; This is because “drugs act on a specific target, such as an enzyme, a receptor, or a transporter.
The preferable action of a drug is specific, that is, it acts on a unique target and induces a strong effect.” [ ] “This is. Regulation of gene expression, or gene regulation, includes a wide range of mechanisms that are used by cells to increase or decrease the production of specific gene products (protein or RNA).Sophisticated programs of gene expression are widely observed in biology, for example to trigger developmental pathways, respond to environmental stimuli, or adapt to new food sources.
Mis-Expression of a Cranial Neural Crest Cell-Specific Gene Program in Cardiac Neural Crest Cells Modulates HAND Factor Expression, Causing Cardiac Outflow Tract Phenotypes by Joshua W. Vincentz 1,*, David E. Clouthier 2 and Anthony B.
Firulli 1,*.The book provides an intensive overview on exercise for cardiovascular disease prevention and treatment, from basic research to clinical practice. The volume firstly summarizes the acute and Author: Junjie Xiao. Study inclusion criteria were: 1) microarray gene expression profiling must be performed on a related, common elderly health, or mental health disorder; 2) RNA was extracted from whole blood or a component of blood; 3) study must contain at least ten human subjects; and 4) data was generated on either the Illumina or Affymetrix microarray Author: Hamel Patel, Hamel Patel, Raquel Iniesta, Daniel Stahl, Richard J.B.
Dobson, Stephen J. Newhouse.